An article at MedPage Today: Rheumatology says, according to results of a U.S. national study, that the rate of hospitalization for serious infection for patients with Systemic Lupus Erythematosus (SLE):
  1. is greater than for patients without SLE,
  2. is accelerating over past decades,
  3. is accelerating faster than for patients without SLE.


The article reports that, "the rates of hospitalization for pneumonia, urinary tract infection, sepsis, skin infections, and opportunistic infections among SLE patients were more than 12 times higher than for non-SLE patients." (Emphasis added by me... not panicking.)

The study being reported on was published in Arthritis Care & Research journal of the American College of Rheumatology

I used to think, glibly, that the over active Lupus immune system would fight off infections better, but speculation in this report is that treatment of Lupus with immunosuppressive therapies may make an SLE patient more susceptible to serious infection. All the more reason for the pneumonia vaccine shot...?