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View Full Version : Too Many Immune Cells May be Behind Lupus



Dr. Mike
3.9.08, 1:27 AM
Saint Louis University School of Medicine has released findings that immune cells that would normally die in healthy people accumulate in bodies of patients who have lupus and contribute to the disease, according to new Saint Louis University research published in the Feb. 15 issue of Immunity.
The finding is important because it tells us more about how lupus develops and suggests a strategy for treating the autoimmune disease, said Harris Perlman, Ph.D., associate professor of molecular microbiology and immunology at Saint Louis University and senior author of the study.
"We want to eliminate those hyperactive immune cells that lead to continuation of the disease but maintain infection-fighting white blood cells," Perlman said. "This will restore the balance of cells in the immune system, which has become very skewed in lupus patients."
It is estimated that between 1.5 and 2 million Americans have some form of lupus, which can damage the kidneys, heart, joints, skin, lungs, blood vessels, liver and nervous system.
In those who have an autoimmune disease such as lupus, the cells in the immune system become confused. Instead of attacking only infected cells or foreign bodies, they turn ultra-vigilant and attack the body's own normal cells and tissues, causing inflammation, pain and injuries.



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